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NEUROLOGY 2004;63:206-207
© 2004 American Academy of Neurology


Views & Reviews

West Nile virus and "poliomyelitis"

James J. Sejvar, MD

From the Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta GA.

Address correspondence and reprint requests to Dr. James J. Sejvar, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS A-39, Atlanta, GA 30333; e-mail: zea3{at}cdc.gov

West Nile virus (WNV) has recently been associated with a syndrome of acute flaccid paralysis. Most cases of WNV-associated weakness have clinical, histopathologic, and electrophysiologic characteristics indistinguishable from those of poliomyelitis caused by infection with poliovirus. There is debate about the nomenclature of this manifestation of WNV infection. An historical perspective of the term "poliomyelitis" suggests that the term "WNV poliomyelitis" seems appropriate, but members of the neurologic and infectious disease communities should engage in discussion regarding the terminology of this syndrome.


Received November 12, 2003. Accepted in final form February 27, 2004.




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