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NEUROLOGY 2004;63:382-384
© 2004 American Academy of Neurology
Brief Communications

Neuro-Behcet disease with predominant involvement of the brainstem

Seyed M. Mirsattari, MD FRCPC, Gregory J. McGinn, MD FRCPC and William C. Halliday, MD FRCPC

From the Department of Clinical Neurological Sciences (Dr. Mirsattari), University of Western Ontario, London, Ontario, Canada; Department of Radiology (Dr. McGinn), University of Manitoba, Winnipeg, Manitoba, Canada; and Department of Pathology (Dr. Halliday), University of Toronto, Ontario, Canada.

Address correspondence and reprint requests to Dr. Seyed M. Mirsattari, 10-OP3, Department of Clinical Neurological Sciences, London Health Sciences Centre, 339 Windermere Road, London, Ontario, Canada N6A 5A5; e-mail: smmirsat{at}uwo.ca

We report a patient with relapsing-remitting meningoencephalitis secondary to neuro-Behcet disease which resulted in recurrent brainstem encephalitis. MRI revealed increased signal intensity on the proton density and T2-weighted images and gadolinium enhancement during relapses. Autopsy revealed acute on chronic meningoencephalomyelitis involving the entire CNS, which was most marked in the brainstem.

Received January 6, 2004. Accepted in final form March 8, 2004.




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