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From the Departments of Clinical Epidemiology and Biostatistics (Drs. Lindeboom and de Haan, and R. Holman) and Neurology (Drs. Schmand and Vermeulen), Academic Medical Center, Amsterdam; and Department of Psychology (Dr. Schmand), University of Amsterdam, The Netherlands.
Address correspondence and reprint requests to Dr. R. Lindeboom, Department of Clinical Epidemiology and Biostatistics, J2212, Academic Medical Center, PO Box 22660, 1100 DD Amsterdam, The Netherlands; e-mail: r.lindeboom{at}amc.uva.nl
To enhance the score interpretation and practicality of the Cambridge Cognitive Examination (CAMCOG) neuropsychological test, the authors used item response theory (IRT) to calibrate the difficulty of the items using the scores of 797 subjects. Forty-seven items fitted the IRT model. Score agreement with equally difficult short forms was excellent. The practicality and interpretability of the CAMCOG was improved, while the diagnostic accuracy of the short forms was similar to that of the original 60-item instrument.
Received August 18, 2003. Accepted in final form March 17, 2004.
Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the August 10 issue to find the title link for this article.
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