HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Correspondence: Submit a response Correspondence: View responses Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Manconi, M. Articles by Granieri, E. Search for Related Content PubMed PubMed Citation Articles by Manconi, M. Articles by Granieri, E. Related Collections Endocrine All Sleep Disorders Restless legs syndrome

Restless legs syndrome and pregnancy

From the Section of Neurological Clinic (Drs. Govoni, De Vito, Economou, Cesnik, Casetta, and Granieri) and Section of Gynecology and Obstetrics (Dr. Mollica), Ferrara University, Italy; Sleep Disorders Center, Department of Neurology (Drs. Manconi and Ferini-Strambi), Vita-Salute University, IRCCS H.S. Raffaele, Milan, Italy.

Address correspondence and reprint requests to Dr. Mauro Manconi, Sleep Disorders Center, Department of Neurology, Vita-Salute University, IRCCS San Raffaele Hospital, Via Stamira d’Ancona 20, 20127 Milan, Italy; e-mail: manconi.mauro{at}hsr.it

Objective: To perform a large and detailed epidemiologic study on restless legs syndrome (RLS) during pregnancy and the puerperium.

Methods: A structured clinical interview, assessing symptoms since the beginning of pregnancy, was performed to a population of 642 pregnant women at the time of delivery and at follow-up evaluation (1, 3, and 6 months after delivery). Main hematologic tests were also evaluated. A woman was considered affected if she met the International RLS Study Group criteria for RLS diagnosis.

Results: Twenty-six percent of women were affected by RLS during their pregnancy. The disease was strongly related to the third trimester of pregnancy and tended to disappear reaching the time of delivery. Affected women presented lower values of hemoglobin and mean corpuscular volume compared with healthy subjects (both groups received the same supplemental iron and folate therapy).

Conclusions: Pregnancy is associated with transient restless legs syndrome.

Received February 3, 2004. Accepted in final form May 21, 2004.

This article has been cited by other articles:

				C A Hayes, J R Kingsley, K R Hamby, and J Carlow The effect of endovenous laser ablation on restless legs syndrome Phlebology, June 1, 2008; 23(3): 112 - 117. [Abstract] [Full Text] [PDF]

				Sleep Disturbances in Women Journal Watch Women's Health, April 10, 2008; 2008(410): 1 - 1. [Full Text]

				M. Manconi, M.A. Rocca, L. Ferini-Strambi, P. Tortorella, F. Agosta, G. Comi, and M. Filippi Restless legs syndrome is a common finding in multiple sclerosis and correlates with cervical cord damage Multiple Sclerosis, January 1, 2008; 14(1): 86 - 93. [Abstract] [PDF]

				M. T. Wright Antiemetics, Akathisia, and Pregnancy Psychosomatics, December 1, 2007; 48(6): 461 - 466. [Abstract] [Full Text] [PDF]

				C. E. Gamaldo and C. J. Earley Restless legs syndrome: a clinical update. Chest, November 1, 2006; 130(5): 1596 - 1604. [Abstract] [Full Text] [PDF]

				S. Clemens, D. Rye, and S. Hochman Restless legs syndrome: Revisiting the dopamine hypothesis from the spinal cord perspective. Neurology, July 11, 2006; 67(1): 125 - 130. [Abstract] [Full Text] [PDF]

Correspondence: