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Practice Parameter: Treatment of postherpetic neuralgia

An evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology^*

Address correspondence and reprint requests to the American Academy of Neurology, 1080 Montreal Avenue, St. Paul, MN 55116-2325.

A systematic review of the literature on postherpetic neuralgia was performed. The authors identified studies using the National Library of Medicine’s Medline database and Cochrane Library database. The authors determined absolute reduction rate, number needed to treat (NNT), 95% CI for NNT, and number needed to harm (NNH) for successful therapies of postherpetic neuralgia. Tricyclic antidepressants, gabapentin, pregabalin, opioids, and lidocaine patch were found to be effective in reducing the pain of postherpetic neuralgia.

Received October 3, 2001. Accepted in final form May 20, 2004.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the September 28 issue to find the title link for this article.

*Members of the Quality Standards Subcommittee are listed in the Appendix on page 964.

Approved by the QSS in October 2003 and by the Practice Committee in November 2003. Approved by the AAN Board of Directors in June 2004.

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