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NEUROLOGY 2004;63:1309-1310
© 2004 American Academy of Neurology
Brief Communications

Cluster headache and right-to-left shunt on contrast transcranial Doppler

A case-control study

C. Finocchi, MD, M. Del Sette, MD, S. Angeli, MD, D. Rizzi, MD and C. Gandolfo, PhD

From the Department of Neuroscience, Ophthalmology and Genetics, University of Genova, Italy.

Address correspondence and reprint requests to Dr. Cinzia Finocchi, Department of Neuroscience, Ophthalmology and Genetics, University of Genova, Via De Toni, 5, 16132 Genova, Italy; e-mail: cfinocchi{at}neurologia.unige.it

The authors evaluated the prevalence of right-to-left shunt in 40 subjects with cluster headache (CH) vs 40 subjects without primary headaches or cerebrovascular disease. The diagnosis of shunt was made by means of transcranial Doppler with contrast medium. A shunt was found in 17 CH patients (42.5%) and in 7 controls (17.5%) (p = 0.029; OR = 3.48; 95% CI = 1.13 to 10.69).

Received February 17, 2004. Accepted in final form May 26, 2004.




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