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NEUROLOGY 2005;64:1771-1774
© 2005 American Academy of Neurology
Brief Communications

Adult-onset epilepsy in focal cortical dysplasia of Taylor type

A. M. Siegel, MD, G. D. Cascino, MD, C. E. Elger, MD, O. Devinsky, MD, R. Laff, MD, S. Najjar, MD, M. R. Sperling, MD, G. LoRusso, MD, M. Cossu, MD, H. Urbach, MD, E. Aronica, MD, F. B. Meyer, MD, B. W. Scheithauer, MD, F. Dubeau, MD and F. Andermann, MD

From the Epilepsy Program, Department of Neurology (Dr. Siegel), University of Zurich; the Epilepsy Program and Neurosurgery and Neuropathology (Drs. Cascino, Siegel, Meyer, and Scheithauer), Mayo Clinic, Rochester, MN; Klinik für Epileptologie und Institut für Neuroradiologie (Drs. Elger and Urbach), Universität Bonn, Bonn, Germany; Epilepsy Program (Drs. Devinsky, Laff, and Najjar), New York University; Epilepsy Program (Dr. Sperling), Thomas Jefferson University Hospital, Philadelphia; Ospedale Niguarda-Ca Granda (Drs. Lo Russo and M. Cossu), Milan, Italy; University of Utrecht (Dr. Aronica), the Netherlands; and Montreal Neurological Institute and Hospital (Drs. Dubeau and Andermann), Montreal, Quebec, Canada.

Address correspondence and reprint requests to Adrian M. Siegel, MD, Department of Neurology, University Hospital Zurich, 8091 Zurich, Switzerland; e-mail: adrian.siegel{at}usz.ch

Focal cortical dysplasia of Taylor type (FCDT) usually presents with seizures at an early age, whereas adult onset of epilepsy is uncommon. We reviewed the medical records of 213 patients with FCDT. In 21 patients (10%), age at seizure onset ranged from 18 to 55 years (mean 25.3). The outcome of seizures in patients with FCDT and adult-onset epilepsy seems favorable vs childhood-onset seizures.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the May 24 issue to find the title link for this article.

Received June 15, 2004. Accepted in final form January 31, 2005.




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