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Subacute inflammatory demyelinating polyneuropathy in children

From the Department of Neurology, Royal Children’s Hospital, Parkville, Victoria, Australia.

Address correspondence and reprint requests to Dr Kornberg, Department of Neurology, Royal Children’s Hospital, Flemington Road, Parkville, Victoria, Australia 3052; e-mail: andrew.kornberg{at}rch.org.au

Reported are five children with subacute demyelinating polyneuropathy. All patients had a monophasic disease, progressing over 4 to 8 weeks and characterized by predominantly motor features, areflexia, minimal or no cranial nerve abnormalities, no autonomic or respiratory involvement, elevated CSF protein, electrophysiologic evidence of demyelination, and good response to corticosteroids. A benign course with full recovery was the rule.

Supported by an educational grant from CSL Bioplasma Limited, Victoria, Australia (M.V.R.-C.).

Received August 10, 2004. Accepted in final form February 3, 2005.