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Incidence of contrast nephropathy from cerebral CT angiography and CT perfusion imaging

From the Departments of Neurology (Drs. Josephson and Smith) and Radiology (Dr. Dillon), University of California, San Francisco.

Address correspondence and reprint requests to Dr Smith, Department of Neurology, 505 Parnassus Ave., San Francisco, CA 94143-0114; e-mail: wssmith{at}itsa.ucsf.edu

The incidence of contrast-induced nephropathy was examined in 1,075 patients receiving routine CT angiography and CT perfusion brain imaging at a single institution. Fifty-two patients had a creatinine rise of 0.5 mg/dL. In four patients (0.37%), the administration of IV contrast medium possibly contributed to renal failure. Two patients (0.19%) received temporary hemodialysis during hospitalization. The incidence of contrast nephropathy in neurovascular patients is low.

Received December 3, 2004. Accepted in final form February 11, 2005.

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