Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow CME: Take the course for this article:
 Volume 64, Number 12, June 28, 2005
Right arrow Data Supplement
Right arrow Polish Data Supplement
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Geerts, A. T.
Right arrow Articles by van Donselaar, C. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Geerts, A. T.
Right arrow Articles by van Donselaar, C. A.
Related Collections
Right arrow All Pediatric
Right arrow All Epilepsy/Seizures
Right arrow Antiepileptic drugs
Right arrowRelated Article
NEUROLOGY 2005;64:2136-2138
© 2005 American Academy of Neurology
Brief Communications

Four-year outcome after early withdrawal of antiepileptic drugs in childhood epilepsy

A. T. Geerts, MSc*, J.M.F. Niermeijer, MD*, A. C.B. Peters, MD, PhD, W. F.M. Arts, MD, PhD, O. F. Brouwer, MD, PhD, H. Stroink, MD, E. A.J. Peeters, MD and C. A. van Donselaar, MD, PhD

From the Department of Neurology (Drs. Geerts and Arts), Section Pediatric Neurology, Erasmus Medical Center–Sophia Children’s Hospital, Rotterdam; Departments of Neurology and Neurosurgery (Dr. Niermeijer and van Donselaar) and Pediatric Neurology (Dr. Peters), Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht; Department of Neurology (Dr. Brouwer), University Medical Center Groningen, Groningen; Department of Neurology (Dr. Stroink), St. Elisabeth and Tweesteden Hospital, Tilburg; Department of Pediatric Neurology (Dr. Peeters), MCH Westeinde and Juliana Children’s Hospital, The Hague, The Netherlands.

Address correspondence and reprint requests to Dr van Donselaar, Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, UMC Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands; e-mail: c.a.vandonselaar{at}neuro.azu.nl

Four-year follow-up of children with epilepsy included in a randomized trial of early withdrawal of antiepileptic drugs showed that 51% achieved a terminal remission of at least 2 years without medication and 21% with medication; 15% had seizures during the fourth year. Early medication withdrawal is not recommended as standard practice in children with a rapid response to medication. The authors developed a model to predict outcome if withdrawal is considered.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the June 28 issue to find the title link for this article.

*The first two authors contributed equally to this study.

Supported by the National Epilepsy Fund, Houten, The Netherlands (A72 and A85) as part of the Dutch Study of Epilepsy in Childhood.

Received September 10, 2004. Accepted in final form March 15, 2005.


Related Article

June 28 Highlights
Neurology 2005 64: 1994-1995. [Full Text] [PDF]



This article has been cited by other articles:


Home page
 NeurologyHome page
D. C. Spencer and C. M. Roberts
Stopping seizure medications in children: When is it safe?
Neurology, June 28, 2005; 64(12): E32 - E33.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by AAN Enterprises, Inc.