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 Volume 64, Number 2, January 25, 2005
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NEUROLOGY 2005;64:335-337
© 2005 American Academy of Neurology
Brief Communications

Effect of corticosteroids on short-term and long-term memory

R. Brunner, MD, D. Schaefer, MA, K. Hess, MA, P. Parzer, MA, F. Resch, MD and S. Schwab, MD

From the Departments of Neurology (Dr. Schwab, D. Schaefer and K. Hess) and Child and Adolescent Psychiatry (Drs. Brunner and Resch, P. Parzer), University of Heidelberg, Germany.

Address correspondence and reprint requests to Dr. S. Schwab, Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; e-mail: stefan.schwab{at}med.uni-heidelberg.de

The effect of acute high-dose glucocorticoid therapy on memory function in patients with acute optic neuritis (n = 9) and multiple sclerosis (n = 21) was studied. All patients had reversible impairment of long-term memory functions, whereas measures of short-term memory, attentional functions, and alertness remained unaffected.

See also page 184

Received July 14, 2004. Accepted in final form September 10, 2004.


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