Neurology®
The most widely read and highly cited peer-reviewed Neurology journal
Quick Search
Advanced Search
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kochanski, A.
Right arrow Articles by Nicholson, G. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kochanski, A.
Right arrow Articles by Nicholson, G. A.
Related Collections
Right arrow Peripheral neuropathy
Right arrow All Genetics
Right arrow Genetic linkage
NEUROLOGY 2005;64:533-535
© 2005 American Academy of Neurology
Brief Communications

Mild early onset axonal Charcot-Marie-Tooth disease not linked to other axonal Charcot-Marie-Tooth loci

A. Kochanski, MD, PhD, M. Kennerson, PhD, M. Kawulak, B. Ryniewicz, MD, PhD, K. Rowinska-Marcinska, MD, PhD, G. Walizada, BSc, A. Nowakowski, BSc, I. Hausmanowa-Petrusewicz, MD, PhD and G. A. Nicholson, MD, PhD

From the Neuromuscular Unit (Dr. Kochanski, M. Kawulak, Dr. Rowinska- Marcinska, A. Nowakowski, and Dr. Hausmanowa-Petrusewicz), Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland; University of Sydney Neurobiology Laboratory (Dr. Kennerson, G. Walizada, and Dr. Nicholson), Anzac Research Institute, Concord Hospital, New South Wales, Australia; and Department of Neurology (Drs. Ryniewicz and Rowinska- Marcinska), Medical University, Warsaw, Poland.

Address correspondence and reprint requests to Dr. Andrzej Kochanski, Neuromuscular Unit, Polish Academy of Sciences, Medical Research Centre, Pawinskiego 5, 02-106 Warsaw, Poland; e-mail: andko{at}cmdik.pan.pl

Autosomal dominant axonal Charcot-Marie-Tooth disease type 2 (CMT2) is a heterogeneous group of disorders with seven chromosomal loci mapped in the uncomplicated forms of CMT2. The authors report clinical, electrophysiologic, and genetic analysis of a Polish CMT2 family. Nine known CMT2 gene loci and one MPZ gene locus have been excluded. The authors’ findings suggest that this family represents a novel form of CMT2 disease.

Supported by grant no. 2P05B from the Polish State Committee for Scientific Research and grant no. 153895 from the National Health and Medical Research Council of Australia (G.A.N. and M.K.).

Received April 6, 2004. Accepted in final form September 16, 2004.