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From the Research Institute, Multiple Sclerosis Clinic (Dr. Banwell) and Department of Psychology and Children’s Stroke Program (Dr. Anderson), The Hospital for Sick Children, Toronto, Ontario, Canada.
Address correspondence and reprint requests to Dr. Brenda L. Banwell, Multiple Sclerosis Clinic, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8; e-mail: brenda.banwell{at}sickkids.ca
Little is known about the cognitive sequelae of pediatric-onset multiple sclerosis (MS). Ten pediatric patients with MS were evaluated using a comprehensive neuropsychological battery. Neuropsychological deficits were identified on measures of general cognition, language, visuomotor integration, and verbal and visual memory. Cognitive impairment occurs in children with MS, and those with longer disease duration and younger age at MS onset appear to be at greatest risk.
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