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NEUROLOGY 2005;64:1052-1054
© 2005 American Academy of Neurology
Brief Communications

Sonothrombolysis in acute ischemic stroke for patients ineligible for rt-PA

Jürgen Eggers, MD, Günter Seidel, MD, Björn Koch, BSc and Inke R. König, PhD

From the Department of Neurology (Drs. Eggers and Seidel, B. Koch) and the Institute of Medical Biometry and Statistics (Dr. König), University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.

Address correspondence and reprint requests to Dr. Günter Seidel, Department of Neurology, University Hospital, Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23438 Lübeck, Germany; e-mail: guenter.seidel{at}neuro.uni-luebeck.de

The authors studied the effect of transcranial ultrasound on patients with acute middle cerebral artery occlusion and contraindications for thrombolysis. Fifteen consecutive subjects were randomized for insonation over 1 hour or for inclusion in a control group. By day 4, recanalization and neurologic improvement occurred more frequently in the target group. Ultrasound-induced acceleration of clot dissolution may be an option for patients with contraindications for recombinant tissue plasminogen activator.

Received June 18, 2004. Accepted in final form November 8, 2004.

See Commentary, page 935


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Neurology 2005 64: 935. [Full Text] [PDF]



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Correspondence:

Read all Correspondence

Sonothrombolysis in acute ischemic stroke for patients ineligible for rt-PA
Jaroslaw Krejza, et al.
Neurology Online, 13 Jun 2005 [Full text]
Reply to Krejza et al
Seidel Günter, et al.
Neurology Online, 13 Jun 2005 [Full text]