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From the Departments of Neurology (Drs. Hasbani, Sansing, Asbury, and Bird) and Emergency Medicine (Dr. Perrone), University of Pennsylvania School of Medicine, Philadelphia, PA.
Address correspondence and reprint requests to Dr. M.J. Hasbani, Department of Neurology, University of Pennsylvania School of Medicine, 3400 Spruce St., 3 West Gates, Philadelphia, PA 19104-4283; e-mail: hasbani2001{at}yahoo.com
The authors report a 24-year-old man who developed encephalopathy and rapid quadriplegia following ingestion of a solution containing diethylene glycol (DEG). As quadriparesis evolved, motor response amplitudes were markedly reduced with preserved conduction velocities. Studies during clinical recovery revealed marked motor conduction velocity slowing and prolonged distal latencies. These data indicate that DEG intoxication may cause a primary acute axonal sensorimotor polyneuropathy with demyelinating physiology during recovery.
Received September 19, 2004. Accepted in final form December 13, 2004.
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G. P. Daubert, A. Katiyar, J. Wilson, L. Baltarowich, M.J. Hasbani, L. Sansing-Hachmann, J. Perrone, A.K. Asbury, and S.J. Bird Encephalopathy and peripheral neuropathy following diethylene glycol ingestion Neurology, March 14, 2006; 66(5): 782 - 783. [Full Text] [PDF] |
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