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Volume 64, Number 8, April 26, 2005
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NEUROLOGY 2005;64:1468-1470
© 2005 American Academy of Neurology


Brief Communications

Neuropathy resembling CIDP in patients receiving tumor necrosis factor-{alpha} blockers

C. Richez, MD, P. Blanco, MD, A. Lagueny, MD, T. Schaeverbeke, MD, PhD and J. Dehais, MD

From the Service de Rhumatologie (Drs. Richez, Schaeverbeke, and Dehais) and Service d’Immunologie (Dr. Blanco), Groupe Hospitalier Pellegrin, CHU de Bordeaux, Bordeaux, and Service de Neurologie (Dr. Lagueny), Hopital Haut-Leveque, CHU de Bordeaux, Pessac, and Université Bordeaux 2 (Drs. Richez, Blanco, Lagueny, Schaeverbeke, and Dehais), Bordeaux, France.

Address correspondence and reprint requests to Dr. C. Richez, Service de Rhumatologie, Hôpital Pellegrin, Place Amélie Raba Léon, 33076 Bordeaux Cedex, France; e-mail: christophe.richez{at}club-internet.fr

Tumor necrosis factor-{alpha} (TNF{alpha}) blockers are effective in the treatment of inflammatory arthritis but can induce autoimmune disorders including multiple sclerosis. Described are two patients who developed chronic inflammatory demyelinating polyneuropathy after initiation of anti-TNF{alpha} treatment.


Funded by: Société Française de Rhumatologie.

Received October 27, 2004. Accepted in final form December 30, 2004.


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