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From the Department of Neurology, Erasmus MC, Rotterdam, The Netherlands.
Address correspondence and reprint requests to Dr. Liselotte Ruts, Erasmus MC (Faculty), Department of Neurology, Room Ee-2230, PO Box 1738, 3000 DR Rotterdam, The Netherlands; e-mail: l.ruts{at}erasmusmc.nl
GuillainBarré syndrome (GBS) patients may worsen after initial treatment (treatment-related fluctuation [TRF]). It is difficult to distinguish GBS-TRF from chronic inflammatory demyelinating polyneuropathy with acute onset (A-CIDP). The authors compared 13 patients with A-CIDP with 11 patients with GBS-TRF and concluded that A-CIDP should be suspected when a patient with GBS deteriorates after 9 weeks from onset or when deterioration occurs three times or more. Maintenance treatment should then be considered.
Received December 16, 2004. Accepted in final form March 28, 2005.
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