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From the Centre Hospitalier de lUniversité de Montréal (C. Auger and Dr. Duquette) and Hôpital du Sacré-Cæur de Montreal (Dr. Montplaisir), Montreal, Quebec, Canada.
Address correspondence and reprint requests to Dr. Pierre Duquette, Hôpital Notre-Dame du CHUM, 1560 Sherbrooke Street East (H-3135), Montreal, Quebec, Canada, H2L 4K8; e-mail: pierre.duquette.chum{at}ssss.gouv.qc.ca
The authors evaluated the co-occurrence of multiple sclerosis (MS) and restless legs syndrome (RLS) using an RLS questionnaire. They evaluated 200 patients with MS, 100 with rheumatoid arthritis (RA), and 100 controls, all French-Canadians. They found that 37.5% of MS patients, 31% of RA patients, and 16% of controls fulfilled the criteria for RLS. MS can cause RLS, or MS and RLS may have common susceptibility factors.
Supported (in small part) by an unrestricted grant from Boehringer Ingelheim Canada (manufacturers of pramipexole), and by the Quebec Division of the Multiple Sclerosis Society of Canada.
Received April 18, 2005. Accepted in final form August 9, 2005.
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