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NEUROLOGY 2005;65:1657-1660
© 2005 American Academy of Neurology
Brief Communications

H215O or 13NH3 PET and electromagnetic tomography (LORETA) during partial status epilepticus

D. Zumsteg, MD, R. A. Wennberg, MD, MSc, FRCPC, V. Treyer, MD, A. Buck, MD and H. G. Wieser, MD

From the Krembil Neuroscience Centre (Drs. Zumsteg and Wennberg), Toronto Western Hospital, University of Toronto, Toronto, Canada; and the Departments of Nuclear Medicine (Drs. Treyer and Buck) and Neurology (Dr. Wieser), University Hospital Zurich, Zurich, Switzerland.

Address correspondence and reprint requests to Dr. Dominik Zumsteg, Krembil Neuroscience Centre, Toronto Western Hospital, 5W-425, University of Toronto, 399 Bathurst St., Toronto ON M5T 2S8, Canada; e-mail: dzumsteg{at}uhnres.utoronto.ca.

The authors evaluated the feasibility and source localization utility of H215O or 13NH3 PET and low-resolution electromagnetic tomography (LORETA) in three patients with partial status epilepticus (SE). Results were correlated with findings from intraoperative electrocorticographic recordings and surgical outcomes. PET studies of cerebral blood flow and noninvasive source modeling with LORETA using statistical nonparametric mapping provided useful information for localizing the ictal activity in patients with partial SE.

Supported by the Swiss National Science Foundation (grant PA00A-101502).

Disclosure: The authors report no conflicts of interest.

Received May 31, 2005. Accepted in final form August 10, 2005.




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