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Is hospitalization after TIA cost-effective on the basis of treatment with tPA?

From the Departments of Neurology (Dr. Nguyen-Huynh) and Epidemiology (Dr. Johnston), University of California, San Francisco.

Address correspondence and reprint requests to Dr. S. Claiborne Johnston, UCSF, Department of Neurology, 505 Parnassus Street, Box 0114, San Francisco, CA 94143-0114; e-mail: clay.johnston{at}ucsfmedctr.org

A 24-hour hospitalization for TIA could be cost-effective simply by increasing the likelihood that patients will receive tissue plasminogen activator if a stroke occurs. The authors performed a cost-utility analysis of 24-hour hospitalization for patients diagnosed with recent TIA. The overall cost-effectiveness ratio was $55,044 per quality-adjusted life-year, a value considered borderline cost-effective. For patients with higher risk of stroke, admission was cost-effective.

Disclosure: The authors report no conflicts of interest.

Received May 10, 2005. Accepted in final form August 24, 2005.

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