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From the Departments of Neurosurgery (Dr. Wang), Neurology (Drs. W.-N. Chang, Huang, and Lu), Radiology (Dr. Lui), and Otorhinolaryngology (Dr. Peng), Chang Gung Memorial Hospital, Department of Biology (Dr. H.-W. Chang), National Sun Yat-Sen University, and Department of Neurosurgery (Dr. Liliang), E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.
Address correspondence and reprint requests to Dr. C.-H. Lu, Department of Neurology, Chang Gung Memorial Hospital, 123, Ta Pei Road, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan; e-mail: chlu99{at}ms44.url.com.tw
Eight patients who had sensorineural hearing loss (SNHL) associated with cryptococcal meningitis were studied. After a minimum 3-year follow-up, one had died. Among the seven survivors, three had improved, two stabilized, and two progressed. Predictive factors included visual disturbance, meningeal enhancements on MRI, and a CSF cryptococcal antigen titer of >1:1,024. SNHL accounted for 30.8% (8/26) of cryptococcal meningitis patients in our study.
Received September 1, 2004. Accepted in final form April 13, 2005.
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