Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Koch, G.
Right arrow Articles by Centonze, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Koch, G.
Right arrow Articles by Centonze, D.
Related Collections
Right arrow Parkinson's disease/Parkinsonism
Right arrow TMS
NEUROLOGY 2005;65:623-625
© 2005 American Academy of Neurology
Brief Communications

rTMS of supplementary motor area modulates therapy-induced dyskinesias in Parkinson disease

G. Koch, MD, L. Brusa, MD, C. Caltagirone, MD, A. Peppe, MD, M. Oliveri, MD, P. Stanzione, MD and D. Centonze, MD

From the Fondazione Santa Lucia IRCCS (Drs. Koch, Brusa, Caltagirone, Peppe, Oliveri, Stanzione, and Centonze), Rome, Clinica Neurologica (Drs. Koch, Brusa, Caltagirone, Stanzione, and Centonze), Dipartimento di Neuroscienze, Università di Tor Vergata, Rome, and Dipartimento di Psicologia (Dr. Oliveri), Università di Palermo, Italy.

Address correspondence and reprint requests to Dr. G. Koch, Fondazione Santa Lucia, IRCCS, Laboratorio di Neurologia Clinica e Comportamentale, Via Ardeatina 306, 00179 Roma, Italy; e-mail: Giakoch{at}libero.it.

The neural mechanisms and circuitry involved in levodopa-induced dyskinesia are unclear. Using repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) in a group of patients with advanced Parkinson disease, the authors investigated whether modulation of SMA excitability may result in a modification of a dyskinetic state induced by continuous apomorphine infusion. rTMS at 1 Hz was observed to markedly reduce drug-induced dyskinesias, whereas 5-Hz rTMS induced a slight but not significant increase.

Disclosure: The authors report no conflicts of interest.

Received February 9, 2005. Accepted in final form April 18, 2005.




This article has been cited by other articles:


Home page
 NeurologyHome page
G. Koch, L. Brusa, F. Carrillo, E. Lo Gerfo, S. Torriero, M. Oliveri, P. Mir, C. Caltagirone, and P. Stanzione
Cerebellar magnetic stimulation decreases levodopa-induced dyskinesias in Parkinson disease
Neurology, July 14, 2009; 73(2): 113 - 119.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
C. W. Olanow, M. B. Stern, and K. Sethi
The scientific and clinical basis for the treatment of Parkinson disease (2009)
Neurology, May 26, 2009; 72(21_Supplement_4): S1 - S136.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
A. Wagle-Shukla, M. J. Angel, C. Zadikoff, M. Enjati, C. Gunraj, A. E. Lang, and R. Chen
Low-frequency repetitive transcranial magnetic stimulation for treatment of levodopa-induced dyskinesias
Neurology, February 27, 2007; 68(9): 704 - 705.
[Full Text] [PDF]

Home page
 NeurologyHome page
P. M. Rossini and S. Rossi
Transcranial magnetic stimulation: Diagnostic, therapeutic, and research potential
Neurology, February 13, 2007; 68(7): 484 - 488.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by AAN Enterprises, Inc.