Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chai, J.
Right arrow Articles by Logigian, E. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chai, J.
Right arrow Articles by Logigian, E. L.
NEUROLOGY 2005;65:925-927
© 2005 American Academy of Neurology
Brief Communications

Painful small-fiber neuropathy in Sjögren syndrome

J. Chai, MBBS, MRCP(UK), D. N. Herrmann, MBBCh, M. Stanton, MD, R. L. Barbano, MD, PhD and E. L. Logigian, MD

From the Department of Neurology, University of Rochester, NY.

Address correspondence and reprint requests to Dr Logigian, Department of Neurology, University of Rochester School of Medicine and Dentistry, Box 673, 601 Elmwood Ave., Rochester, NY 14642; e-mail: eric_logigian{at}urmc.rochester.edu

Of 20 consecutive patients with Sjögren neuropathy, 16 (80%) presented with burning feet and 12 (60%) with non-length-dependent sensory symptoms. Leg and thigh skin biopsies, performed in 13 patients, including 7 with normal electrophysiology, showed either reduced epidermal nerve fiber (ENF) density or abnormal morphology. ENF loss was frequently non length dependent, suggesting that patients with this disorder commonly have a small-fiber sensory neuronopathy rather than a "dying-back" axonopathy.

Disclosure: The authors report no conflicts of interest.

Received March 15, 2005. Accepted in final form June 8, 2005.




This article has been cited by other articles:


Home page
 J. Neurol. Neurosurg. PsychiatryHome page
K C Gorson, D N Herrmann, R Thiagarajan, T H Brannagan, R L Chin, L J Kinsella, and A H Ropper
Non-length dependent small fibre neuropathy/ganglionopathy
J. Neurol. Neurosurg. Psychiatry, February 1, 2008; 79(2): 163 - 169.
[Abstract] [Full Text] [PDF]

Home page
 BMJHome page
G. Lauria and R. Lombardi
Skin biopsy: a new tool for diagnosing peripheral neuropathy
BMJ, June 2, 2007; 334(7604): 1159 - 1162.
[Full Text] [PDF]

Home page
 Arch NeurolHome page
L. G. Goransson, A. Herigstad, A. B. Tjensvoll, E. Harboe, S. I. Mellgren, and R. Omdal
Peripheral Neuropathy in Primary Sjogren Syndrome: A Population-Based Study
Arch Neurol, November 1, 2006; 63(11): 1612 - 1615.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M Kizawa, K Mori, M Iijima, H Koike, N Hattori, and G Sobue
Intravenous immunoglobulin treatment in painful sensory neuropathy without sensory ataxia associated with Sjogren's syndrome.
J. Neurol. Neurosurg. Psychiatry, August 1, 2006; 77(8): 967 - 969.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by AAN Enterprises, Inc.