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NEUROLOGY 2005;65:1123-1125
© 2005 American Academy of Neurology


Brief Communications

Psychotic disorders in MS: Population-based evidence of an association

Scott B. Patten, MD, PhD, Lawrence W. Svenson, BSc and Luanne M. Metz, MD

From the Department of Community Health Sciences and Department of Psychiatry (Dr. Patten), Department of Community Health Sciences (Mr. Svenson), and Department of Clinical Neurosciences, University of Calgary (Dr. Metz), and University of Calgary Multiple Sclerosis Clinic, Alberta (Dr. Metz); Health Surveillance Branch, Department of Health and Wellness, Government of Alberta (Mr. Svenson); and Department of Public Health Sciences, University of Alberta (Mr. Svenson), Canada.

Address correspondence and reprint requests to Dr. Scott B. Patten, Department of Community Health Sciences and Department of Psychiatry, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1; e-mail: patten{at}ucalgary.ca

Administrative data from a Canadian province were accessed to assess the association of psychotic disorders with multiple sclerosis (MS). Physician-assigned ICD-9-CM codes were used to classify MS and psychotic disorder status. A significant association was observed. Additional research is needed to determine the clinical importance and treatment needs of this population.


Disclosure: The authors report no conflicts of interest.

Received February 3, 2005. Accepted in final form June 15, 2005.




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