Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Correspondence:
View responses
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Piovesan, E. J.
Right arrow Articles by Silberstein, S. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Piovesan, E. J.
Right arrow Articles by Silberstein, S. D.
Related Collections
Right arrow All Headache
Right arrow All Clinical trials
Right arrow Trigeminal neuralgia
Right arrow Clinical trials Observational study (Cohort, Case control)
Right arrow Cranial neuropathy
Right arrowRelated Article
NEUROLOGY 2005;65:1306-1308
© 2005 American Academy of Neurology
Brief Communications

An open study of botulinum-A toxin treatment of trigeminal neuralgia

E. J. Piovesan, MD, H. G. Teive, MD, P. A. Kowacs, MD, M. V. Della Coletta, MD, L. C. Werneck, MD, PhD and S. D. Silberstein, MD, FACP

From the Headache Unit, Neurology Division, Internal Medicine Department, Hospital de Clinicas da Universidade Federal do Parana, Curitiba, Brazil (Drs. Piovesan, Teive, Kowacs, Della Coletta, and Werneck); and Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA (Dr. Silberstein).

Address correspondence and reprint requests to Dr. Elcio J. Piovesan, Headache Unit, Neurology Division, Internal Medicine Department, Hospital de Clinicas da Universidade Federal do Parana, Rua Joinvile—2526, Sao Jose dos Pinhais, PR Brazil 83020 000; e-mail: piovesan1{at}hotmail.com or piovesan{at}avalon.sul.com.br

Thirteen subjects with trigeminal neuralgia were treated with botulinum-A neurotoxin (BoNT/A) in an open-label pilot study. After BoNT/A, visual analog scale score, surface area of pain, and therapeutic coefficient were reduced in all patients and for all branch trigeminal nerves studied. Therefore, BoNT/A is an efficient treatment. There were no major side effects. A placebo-controlled clinical trial is needed to confirm these findings.

Disclosure: The authors report no conflicts of interest.

Received October 12, 2004. Accepted in final form July 8, 2005.


Related Article

October 25 Highlights
Neurology 2005 65: 1148-1149. [Full Text] [PDF]



This article has been cited by other articles:


Home page
 NeurologyHome page
R. Y. Yuan, J. J. Sheu, J. M. Yu, W. T. Chen, I. J. Tseng, H. H. Chang, and C. J. Hu
Botulinum toxin for diabetic neuropathic pain: A randomized double-blind crossover trial
Neurology, April 28, 2009; 72(17): 1473 - 1478.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
S. R. Brenner, B. Voller, T. Sycha, B. Gustorff, G. Kranz, E. Auff, J. M. Zakrzewska, J. Cohen, J. Brown, J. Alksne, et al.
An open study of botulinum-A toxin treatment of trigeminal neuralgia.
Neurology, May 9, 2006; 66(9): 1458 - 1459.
[Full Text] [PDF]

Correspondence:

Read all Correspondence

An open study of botulinum-A toxin treatment of trigeminal neuralgia
Steven R Brenner
Neurology Online, 16 Jan 2006 [Full text]
An open study of botulinum-A toxin treatment of trigeminal neuralgia
Joanna M. Zakrzewska, et al.
Neurology Online, 16 Jan 2006 [Full text]
Reply from the Authors
Elcio Juliato Piovesan, et al.
Neurology Online, 16 Jan 2006 [Full text]
An open study of botulinum-A toxin treatment of trigeminal neuralgia
Bernhard Voller, et al.
Neurology Online, 16 Jan 2006 [Full text]

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by AAN Enterprises, Inc.