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NEUROLOGY 2005;65:1316-1318
© 2005 American Academy of Neurology
Brief Communications

Treatment delay and the risk of prolonged status epilepticus

K. Eriksson, MD, PhD, P. Metsäranta, MD, H. Huhtala, MSc, A. Auvinen, MD, PhD, A. -L. Kuusela, MD, PhD and M. Koivikko, MD, PhD

From the Pediatric Research Centre (Drs. Eriksson, Metsäranta, Koivikko), Medical School, University of Tampere and Tampere University Hospital, Department of Pediatrics, Pediatric Neurology Unit; Tampere School of Public Health (Drs. Huhtala, Auvinen), University of Tampere; Department of Pediatrics (Dr. Kuusela), Pediatric Intensive Care Unit, Tampere University Hospital, Tampere, Finland.

Address correspondence and reprint requests to Dr. K. Eriksson, Pediatric Research Centre, FinnMedi 3, 3rd Floor, 3-118, Medical School, 33014 University of Tampere, Finland; e-mail: kai.eriksson{at}uta.fi

Factors contributing to the duration of a single convulsive seizure >5 minutes were analyzed in 157 children. The medically treated episodes were compared with seizure episodes resolving without treatment (n = 27). Major differences were in age (p = 0.016) and etiology (p = 0.003), and the association between treatment delay and response became significant after 30 minutes when this was analyzed as a single variable (p = 0.003) in Cox regression analysis.

Disclosure: The authors report no conflicts of interest.

Received October 29, 2004. Accepted in final form July 5, 2005.


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