Neurology®
The most widely read and highly cited peer-reviewed Neurology journal
Quick Search
Advanced Search
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Video
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Economides, J. R.
Right arrow Articles by Horton, J. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Economides, J. R.
Right arrow Articles by Horton, J. C.
Related Collections
Right arrow All Immunology
Right arrow All Neuro-ophthalmology
Right arrow Ocular motility
Right arrow Stiff person syndrome
NEUROLOGY 2005;65:1462-1464
© 2005 American Academy of Neurology
Brief Communications

Eye movement abnormalities in stiff person syndrome

John R. Economides, PhD and Jonathan C. Horton, MD, PhD

From the Beckman Vision Center, University of California, San Francisco, CA.

Address correspondence and reprint requests to Dr. Jonathan C. Horton, Beckman Vision Center, University of California San Francisco, 10 Koret Way, San Francisco, CA, 94143-0730; e-mail: horton{at}itsa.ucsf.edu.

The authors describe a 38-year-old woman with stiff person syndrome (SPS) and gaze-holding nystagmus, limited abduction, vertical and horizontal ocular misalignment, deficient smooth pursuit, and impaired saccade initiation. There was no evidence of ocular myasthenia, indicating that abnormalities of ocular motor function can occur as a primary manifestation of SPS, perhaps from depletion of GABA.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the November 8 issue to find the title link for this article.

Supported by the National Eye Institute (EY015343, EY10217, and EY02162), the Larry L. Hillblom Foundation, and Research to Prevent Blindness.

Disclosure: The authors report no conflicts of interest.

Received April 1, 2005. Accepted in final form July 12, 2005.




This article has been cited by other articles:


Home page
 NeurologyHome page
B. Oskarsson, V. Pelak, D. Quan, D. Hall, C. Foster, and S. Galetta
STIFF EYES IN STIFF-PERSON SYNDROME
Neurology, July 29, 2008; 71(5): 378 - 380.
[Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
P L Guardado Santervas, A Arjona Padillo, P Serrano Castro, J Olivares Romero, J Rubi Callejon, G Alonso Verdegay, and A Huete Hurtado
Stiff person syndrome (SPS), a basal ganglia disease? Striatal MRI lesions in a patient with SPS
J. Neurol. Neurosurg. Psychiatry, June 1, 2007; 78(6): 657 - 659.
[Full Text] [PDF]

Home page
 NeurologyHome page
C. R. Gordon, A. Z. Zivotofsky, T. Siman-Tov, N. Gadoth, and M. C. Dalakas
Stiff person syndrome with cerebellar disease and high-titer anti-GAD antibodies
Neurology, April 3, 2007; 68(14): 1161 - 1161.
[Full Text] [PDF]