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NEUROLOGY 2005;65:1467-1470
© 2005 American Academy of Neurology
Brief Communications

Ventrolateral medullary compression in hypertensive patients with hemifacial spasm

L. L. Chan, MD, Y. L. Lo, MD, E. Lee, BSc, S. Fook-Chong, MSc and E. K. Tan, MD

From the Departments of Neurology (Dr. Lo and Tan, Ms. Lee), Diagnostic Radiology (Dr. Chan, Ms. Lee), and Clinical Research (Ms. Fook-Chong), Singapore General Hospital, National Neuroscience Institute (Drs. Lo and Tan), SingHealth (Dr. Tan), Republic of Singapore.

Address correspondence and reprint requests to Dr. Eng-King Tan, Department of Neurology, Singapore General Hospital, Outram Road, Singapore 169608, Republic of Singapore; e-mail: gnrtek{at}sgh.com.sg.

In a patient-controlled study, the authors demonstrated a significantly higher prevalence of rostral ventrolateral medulla (VLM) compression in hypertensive patients with hemifacial spasm (HFS) compared with age-, sex-, race-, disease duration–, and disease severity–matched normotensive patients with HFS (p = 0.02). Hypertensive HFS patients were more likely to have a greater severity of neurovascular compression at the VLM compared with normotensive HFS patients (p = 0.008). VLM compression is associated with risk of hypertension in this study population.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the November 8 issue to find the title link for this article.

Supported by a grant from the National Medical Research Council.

Disclosure: The authors report no conflicts of interest.

Received May 10, 2005. Accepted in final form July 22, 2005.






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