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NEUROLOGY 2006;66:131-132
© 2006 American Academy of Neurology
Brief Communications

Upward gaze–evoked nystagmus with organoarsenic poisoning

Kiyotaka Nakamagoe, MD, PhD, Kazuhiro Ishii, MD, PhD, Akira Tamaoka, MD, PhD and Shin’ichi Shoji, MD, PhD

From the Department of Neurology, Ryugasaki Saiseikai Hospital, Ryugasaki, Ibaraki, Japan (K.N.), and Department of Neurology, Institute of Clinical Medicine, University of Tsukuba, Japan (K.N., K.I., A.T., S.S.).

Address correspondence and reprint requests to Dr. Kiyotaka Nakamagoe, Department of Neurology, Ryugasaki Saiseikai Hospital, 1-1 Nakazato, Ryugasaki, Ibaraki, Japan 305-0854; e-mail: k.nakamagoe{at}ryugasaki-hp.org

The authors report assessment of abnormal ocular movements in three patients after organoarsenic poisoning from diphenylarsinic acid. The characteristic and principal sign is upward gaze–evoked nystagmus. Moreover, vertical gaze holding impairment was shown by electronystagmography on direct current recording.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the January 10 issue to find the title link for this article.

Disclosure: The authors report no conflicts of interest.

Received April 7, 2005. Accepted in final form September 24, 2005.






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