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Volume 66, Number 1, January 10, 2006
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NEUROLOGY 2006;66:139-141
© 2006 American Academy of Neurology


Brief Communications

Diagnostic accuracy of trigeminal reflex testing in trigeminal neuralgia

G. Cruccu, MD, A. Biasiotta, MD, F. Galeotti, MD, G. D. Iannetti, PhD, A. Truini, PhD and G. Gronseth, MD

From the Department of Neurological Sciences (G.C., A.B., F.G., A.T.), La Sapienza University, Rome, Italy; Department of Human Anatomy and Genetics (G.D.I.), Oxford University, Oxford, United Kingdom; Department of Neurology (G.G.), University of Kansas, Kansas City, KS.

Address correspondence and reprint requests to Dr. Giorgio Cruccu, Dipartimento Scienze Neurologiche, Viale Università 30, 00185 Rome, Italy; e-mail: cruccu{at}uniroma1.it

The authors prospectively studied 120 consecutive patients with trigeminal neuralgia (TN) to identify the clinical and laboratory features that most accurately distinguished symptomatic from classic TN. After a standardized evaluation, they identified 24 patients with symptomatic TN. Age, sensory examination, and affected division were not useful in the differential diagnosis. In contrast, electrophysiologic testing of trigeminal reflexes accurately distinguished symptomatic from classic TN (sensitivity 96%, specificity 93%).


Disclosure: The authors report no conflicts of interest.

Received July 28, 2005. Accepted in final form October 4, 2005.







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