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NEUROLOGY 2006;66:1745-1746
© 2006 American Academy of Neurology
Brief Communications

Influence of gender on outcomes after intra-arterial thrombolysis for acute ischemic stroke

S. H. Shah, MD, D. S. Liebeskind, MD, J. L. Saver, MD, S. Starkman, MD, F. Vinuela, MD, G. Duckwiler, MD, R. Jahan, MD, D. Kim, MD, N. Sanossian, MD, P. Vespa, MD and B. Ovbiagele, MD

From the Department of Neurology (S.H.S., D.S.L., J.L.S., S.S., D.K., N.S., P.V., B.O.), Stroke Center (D.S.L., J.L.S., S.S., F.V., G.D., R.J., D.K., N.S., P.V., B.O.), Department of Emergency Medicine (S.S.), Department of Radiology (F.V., G.D., R.J.), and Department of Neurosurgery (P.V.), UCLA Medical Center, Los Angeles, CA.

Address correspondence and reprint requests to Dr. Samir H. Shah, Department of Neurology, University of California at Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095; e-mail: SHShah{at}mednet.ucla.edu

Recent data suggest that women obtain greater benefit than men from IV fibrinolysis for acute ischemic stroke. It is unknown whether this gender–thrombolysis advantage extends to those treated with intra-arterial (IA) thrombolysis. The authors evaluated the independent effect of gender among ischemic stroke patients treated with IA fibrinolysis and found no differences in short-term clinical and angiographic outcomes between men and women who received IA thrombolysis for acute ischemic stroke.

Disclosure: The authors report no conflicts of interest.

Received December 16, 2005. Accepted in final form February 21, 2006.




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M. Arnold, L. Kappeler, K. Nedeltchev, C. Brekenfeld, U. Fischer, B. Keserue, L. Remonda, G. Schroth, and H. P. Mattle
Recanalization and Outcome After Intra-Arterial Thrombolysis in Middle Cerebral Artery and Internal Carotid Artery Occlusion: Does Sex Matter?
Stroke, April 1, 2007; 38(4): 1281 - 1285.
[Abstract] [Full Text] [PDF]


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