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From the Johns Hopkins Outpatient Center (V.C.), Baltimore, MD; Lutheran Medical Office (J.C.S.), Fort Wayne, IN; Indiana University (J.K.), Indianapolis; and Stanford University (Y.T.S.), Stanford, CA.
Address correspondence and reprint requests to the American Academy of Neurology, 1080 Montreal Avenue, Saint Paul, MN 55116; e-mail: rsikka{at}aan.com
Surgical decompression at the site of anatomic narrowing has been promoted as an alternative treatment for patients with symptomatic diabetic neuropathy. Systematic review of the literature revealed only Class IV studies concerning the utility of this therapeutic approach. Given the current evidence available, this treatment alternative should be considered unproven (Level U). Prospective randomized controlled trials with standard definitions and outcome measures are necessary to determine the value of this therapeutic intervention.
Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the June 27 issue to find the title link for this article.
Approved by the Therapeutics and Technology Assessment Subcommittee on October 23, 2005; by the Practice Committee on April 5, 2006; and by the AAN Board of Directors on May 4, 2006.
Disclosure: The authors report no conflicts of interest.
Received December 12, 2005. Accepted in final form March 16, 2006.
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