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Silent microbleeds are associated with volume of primary intracerebral hemorrhage

From the Department of Neurology; Neuroscience Research Institute, SNUMRC and Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.

Address correspondence and reprint requests to Dr. Jae-Kyu Roh, Department of Neurology, Seoul National University Hospital, 28 Yongon-dong, Jongno-gu, Seoul, 110-744, Republic of Korea; e-mail: rohjk{at}snu.ac.kr

The authors performed a correlative radiologic study on the micro-bleeds and volume of intracerebral hemorrhage in the supratentorial ICH patients. In the patients with lobar or putaminal hemorrhage, the hemorrhage volumes increased more than twofold or threefold in the patients with micro-bleeds. Moreover, the presence of microbleeds was an independent risk factor for large-sized hemorrhage. These data show that microbleeds may be associated with a larger ICH volume.

Disclosure: The authors report no conflicts of interest.

Received June 30, 2005. Accepted in final form October 24, 2005.

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