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Short-distance walking speed and timed walking distance: Redundant measures for clinical trials?

From the Neurologic Rehabilitation and Research Program, Department of Neurology, Geffen School of Medicine, University of California Los Angeles.

Address correspondence and reprint requests to Dr. Bruce H. Dobkin, Department of Neurology, University of California Los Angeles, Geffen School of Medicine Reed Neurologic Research Center, 710 Westwood Plaza, Los Angeles, CA 90095; e-mail: bdobkin{at}mednet.ucla.edu

The velocity of a 15-meter walk and walking endurance (distance covered in 6 minutes) are considered distinct outcomes in clinical trials of stroke rehabilitation. Comfortable velocities used for each task in 24 subjects with chronic hemiparesis were not significantly different, however. Although speed and endurance did not reflect different domains of efficacy in outpatients whose usual speed was >0.5 m/s, the fastest feasible 15-meter velocity augmented these measures.

Supported by NIH/NICHD RO1 HD 046740, NIH/NICHD #HD39629, and the Larry L. Hillblom Foundation.

Disclosure: The author reports no conflicts of interest.

Received July 8, 2005. Accepted in final form November 2, 2005.

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