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Neuropsychological deficits in long-term frequent cannabis users

From the Department of Neurology (L.M., P.P.), University Hospital Patras, Patras, Greece; Department of Speech and Language Therapy (A.K.), Higher Technological Institute of Patras, Patras, Greece; and Department of Statistics and Insurance Science (S.M.), University of Piraeus, Piraeus, Greece.

Address correspondence and reprint requests to Dr. Lambros Messinis, Rixinoros 6, Patras 26442, Greece; e-mail: lambros{at}hellasnet.gr

The authors examined neuropsychological functioning in 20 long-term (LT), 20 shorter term (ST) heavy frequent cannabis users, and 24 controls after abstinence for 24 hours prior to testing. LT users performed significantly worse on verbal memory and psychomotor speed. LT and ST users had a higher proportion of deficits on verbal fluency, verbal memory, attention, and psychomotor speed. Specific cognitive domains appear to deteriorate with increasing years of heavy frequent cannabis use.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the March 14 issue to find the title link for this article.

Disclosure: The authors report no conflicts of interest.

Received April 4, 2005. Accepted in final form November 28, 2005.

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Neurology 2006 66: 620-621. [Full Text] [PDF]

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				L. Messinis, P. Papathanasopoulos, A. Feinstein, and O. Ghaffar MULTIPLE SCLEROSIS AND CANNABIS: A COGNITIVE AND PSYCHIATRIC STUDY Neurology, January 6, 2009; 72(1): 100 - 101. [Full Text] [PDF]

				J. Fisk and C. Montgomery Real-world memory and executive processes in cannabis users and non-users J Psychopharmacol, September 1, 2008; 22(7): 727 - 736. [Abstract] [PDF]

				P. Papathanasopoulos, L. Messinis, E. Lyros, A. Kastellakis, and G. Panagis Multiple Sclerosis, Cannabinoids, and Cognition J Neuropsychiatry Clin Neurosci, February 1, 2008; 20(1): 36 - 51. [Abstract] [Full Text] [PDF]

				M. Accordino, C. L. Hart, L. Messinis, and P. Panagiotis Neuropsychological deficits in long-term frequent cannabis users Neurology, November 28, 2006; 67(10): 1902 - 1902. [Full Text] [PDF]

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