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NEUROLOGY 2006;66:917-918
© 2006 American Academy of Neurology
Brief Communications

Multifocal neuropathy due to plasma cell infiltration of peripheral nerves in multiple myeloma

C. Denier, MD, P. Lozeron, MD, D. Adams, MD, D. Decaudin, MD, F. Isnard-Grivaux, MD, C. Lacroix, MD and G. Said, MD

From the Department of Neurology, University Paris XI, Hopital de Bicêtre (C.D., P.L., D.A., C.L., G.S.), Le Kremlin-Bicêtre, Hematology Department, Curie Institute (D.D.); and Hematology Department, Saint-Antoine Hospital (F.I.-G.), Paris, France.

Address correspondence and reprint requests to Dr. Gerard Said, Department of Neurology, Hopital Bicêtre, 94275 Le Kremlin-Bicêtre, France; e-mail: gerard.said{at}bct.aphp.fr.

Patients with multiple myeloma (MM) can manifest a variety of neurologic complications. The authors report two patients who had development of a multifocal neuropathy related to infiltration of peripheral nerves by malignant plasma cells as the only manifestation of a relapse of MM, which was considered in full remission.

Disclosure: The authors report no conflicts of interest.

Received August 29, 2005. Accepted in final form December 2, 2005.






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