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 Volume 66, Number 7, April 11, 2006
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NEUROLOGY 2006;66:1105-1107
© 2006 American Academy of Neurology
Brief Communications

Prolonged but reversible migraine-like episodes long after cranial irradiation

Sonia Partap, MD, Melanie Walker, MD, W. T. Longstreth, Jr, MD, MPH and Alexander M. Spence, MD

From the Division of Pediatric Neurology and Children's Hospital and Regional Medical Center (S.P.) and Department of Neurology (M.W., W.T.L., A.M.S.), University of Washington, Seattle, WA.

Address correspondence and reprint requests to Dr. Alexander M. Spence, Department of Neurology, Box 356465, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195-6465; e-mail: aspence{at}u.washington.edu

The authors describe three patients with prolonged but reversible episodes of severe headaches and focal neurologic deficits developing years after irradiation for cranial neoplasms. Despite extensive evaluations, etiology of episodes in these three and eight other previously reported patients remains undetermined. Whether they all have the same condition is uncertain. Although some had cortical gadolinium enhancement on MRI, all 11 patients returned to baseline over hours to weeks.

Disclosure: The authors report no conflicts of interest.

Received May 16, 2005. Accepted in final form December 20, 2005.


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April 11 Highlights
Neurology 2006 66: 960-961. [Full Text] [PDF]



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A. Pruitt, J. Dalmau, J. Detre, A. Alavi, and M. R. Rosenfeld
Episodic neurologic dysfunction with migraine and reversible imaging findings after radiation
Neurology, August 22, 2006; 67(4): 676 - 678.
[Abstract] [Full Text] [PDF]


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