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From the Department of Neurology, Mayo Clinic, Jacksonville, FL.
Address correspondence and reprint requests to Dr. Kurt A. Jaeckle, Department of Neurology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224; e-mail: jaeckle.kurt{at}mayo.edu
The authors describe the clinical and diagnostic characteristics of four patients with metastatic CNS disease presenting in de novo nonconvulsive status epilepticus (NCSE). Treatment with anticonvulsants resulted in resolution of NCSE in two patients and a brief improvement in mental status in the other two patients. NCSE should be considered in the differential diagnosis of acute mental status change in patients with metastatic CNS disease.
Disclosure: The authors report no conflicts of interest.
Received September 26, 2005. Accepted in final form January 13, 2006.
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