Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ortigue, S.
Right arrow Articles by Blanke, O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ortigue, S.
Right arrow Articles by Blanke, O.
Related Collections
Right arrow All Neuropsychology/Behavior
Right arrow Neglect
NEUROLOGY 2006;66:1414-1417
© 2006 American Academy of Neurology

Double dissociation between representational personal and extrapersonal neglect

S. Ortigue, PhD, P. Mégevand, MD, F. Perren, MD, T. Landis, MD and O. Blanke, MD

From Functional Brain Mapping Laboratory (S.O.), University Hospital of Geneva, and Department of Fundamental Neurosciences, University Central Medical School, Geneva, Department of Neurology (S.O., P.M., F.P., T.L., O.B.), University Hospital of Geneva, and Laboratory of Cognitive Neuroscience (O.B.), Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Switzerland.

Address correspondence and reprint requests to Dr. S. Ortigue, Dartmouth Functional Brain Imaging Center, Center for Cognitive Neuroscience, Department of Psychology and Brain Sciences, Dartmouth College, 6162 Moore Hall, Rm. 432, Hanover, NH 03755; e-mail: stephanie.ortigue{at}dartmouth.edu

Background: Although perceptual and representational neglect are frequently associated, the demonstration of a double dissociation between both neglect forms suggests that both rely on different central mechanisms. In addition, perceptual neglect can be selectively observed within personal space or extrapersonal space. However, it is not known whether the latter dissociation also exists in representational neglect.

Methods: The authors investigated this question in two brain-damaged patients with anatomically different lesions sites, using neuropsychological tests specifically designed to assess perceptual and representational neglect in both personal and extrapersonal space.

Results: Patients presented a double dissociation with respect to personal and extrapersonal space in representational neglect.

Conclusions: These data suggest that the cerebral networks that process mental space representation use similar principles of space compartmentalization as those used by cerebral networks processing perceived space.

Supported by the Swiss National Science Foundation (3100-065096.01/2 and 3100-0650232.02; 3100-067874.02) and the Swiss Foundation for Biology and Medicine (1223/PASMA 111563/1).

Disclosure: The authors report no conflicts of interest.

Received September 7, 2005. Accepted in final form January 23, 2006.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by AAN Enterprises, Inc.