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Rehabilitation of limb apraxia improves daily life activities in patients with stroke

From the Neuropsychological Rehabilitation Unit (N.S.), "G.B. Rossi" University Hospital, Verona; Department of Psychology (S.M.A.), University of Rome ("La Sapienza"); "C. Santi" Rehabilitation Centre (F.G., A.C.), Verona; Department of Neurological and Vision Sciences (M.T., A.F., E.C.), Neurorehabilitation Section, University of Verona; and Neurology Unit (M.T.), "Maggiore" University Hospital, Verona, Italy.

Address correspondence and reprint requests to Dr. Nicola Smania, Centro di Rieducazione Funzionale Policlinico G.B. Rossi, Via L.A. Scuro, 10, 37134 Verona, Italy; e-mail: nicola.smania{at}univr.it

We randomly assigned 33 patients with left hemisphere stroke, limb apraxia, and aphasia to an apraxia or a control (aphasia) treatment group. Before and after each treatment, patients underwent a comprehensive neuropsychological testing battery and a caregiver evaluation of patient’s activities of daily life (ADL) independence. Apraxia severity was related with ADL independence. Control (aphasia) treatment improved patients’ language and intelligence performance. Apraxia treatment specifically improved praxic function and ADL.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the December 12 issue to find the title link for this article.

Supported by grants from the Ministero Italiano Universita’ Ricerca and Finanziamento Italiano Ricerca di Base (FIRB), both awarded to Salvatore M. Aglioti.

Disclosure: The authors report no conflicts of interest.

Received December 1, 2005. Accepted in final form August 22, 2006.

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