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 Volume 67, Number 11, December 12, 2006
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NEUROLOGY 2006;67:2060-2062
© 2006 American Academy of Neurology
Brief Communications

Retinopathy in survivors of primary central nervous system lymphoma

Sean A. Grimm, MD, Joachim Yahalom, MD, Lauren E. Abrey, MD and Lisa M. DeAngelis, MD

From the Departments of Neurology (S.A.G., L.E.A., L.M.D.A.) and Radiation Oncology (J.Y.), Memorial Sloan-Kettering Cancer Center, New York, NY.

Address correspondence and reprint requests to Dr. Lisa M. DeAngelis, Memorial Sloan-Kettering Cancer Center, Department of Neurology, 1275 York Avenue, New York, NY 10021; e-mail: deangell{at}mskcc.org

Radiation retinopathy is a well-known complication of irradiation for diseases of the globe, orbit, or neighboring tissues but is rare after whole-brain radiation therapy (WBRT), even though the treatment port includes the posterior retina. We describe five patients with long-term primary CNS lymphoma who were diagnosed with retinopathy several years after treatment with chemotherapy and WBRT.

Disclosure: The authors report no conflicts of interest.

Received February 7, 2006. Accepted in final form August 22, 2006.


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