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NEUROLOGY 2006;67:2070-2072
© 2006 American Academy of Neurology
Brief Communications

A rapid screening battery to identify frontal dysfunction in patients with ALS

Claire Flaherty-Craig, PhD, Paul Eslinger, PhD, Beth Stephens, MA and Zachary Simmons, MD

From the Department of Neurology, Penn State College of Medicine, Penn State Hershey Medical Center, Hershey, PA.

Address correspondence and reprint requests to Dr. Zachary Simmons, Penn State Hershey Medical Center, Department of Neurology, H037, 500 University Drive, Hershey, PA 17033; e-mail: zsimmons{at}psu.edu

We studied the relationship between verbal associative fluency, verbal abstract reasoning, and judgment in ALS using a 20-minute screening evaluation. Deficiencies in these measures were found in 20.0%, 18.6%, and 35.7% of patients with limb-onset ALS and in 37.5%, 25.0%, and 60.0% of patients with bulbar-onset ALS. This simple screen identifies deficits that affect discussions of treatment interventions and end-of-life issues.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the December 12 issue to find the title link for this article.

Disclosure: The authors report no conflicts of interest.

Received December 12, 2005. Accepted in final form August 3, 2006.




This article has been cited by other articles:


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P. Wicks, S. Abrahams, P. N. Leigh, L. H. Goldstein, Z. Simmons, C. Flaherty-Craig, P. Eslinger, and B. Stephens
A RAPID SCREENING BATTERY TO IDENTIFY FRONTAL DYSFUNCTION IN PATIENTS WITH ALS
Neurology, July 3, 2007; 69(1): 118 - 120.
[Full Text] [PDF]

Correspondence:

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A rapid screening battery to identify frontal dysfunction in patients with ALS
Paul J Wicks, et al.
Neurology Online, 10 Mar 2007 [Full text]
Reply from the Authors
Zachary Simmons, et al.
Neurology Online, 10 Mar 2007 [Full text]

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