Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Correspondence:
View responses
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Misra, U. K.
Right arrow Articles by Patel, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Misra, U. K.
Right arrow Articles by Patel, R.
Related Collections
Right arrow Status epilepticus
Right arrow All Epilepsy/Seizures
Right arrow Antiepileptic drugs
NEUROLOGY 2006;67:340-342
© 2006 American Academy of Neurology
Brief Communications

Sodium valproate vs phenytoin in status epilepticus: A pilot study

U. K. Misra, DM, Jayantee Kalita, DM and Rajesh Patel, DM

From the Department of Neurology, Sanjay Gandhi PGIMS, Lucknow, India.

Address correspondence and reprint requests to Dr Misra, Department of Neurology, Sanjay Gandhi PGIMS, Lucknow 226014, India; e-mail: drukmisra{at}rediffmail.com

Sixty-eight patients with convulsive status epilepticus (SE) were randomly assigned to two groups to study the efficacy of sodium valproate (VPA) and phenytoin (PHT). Seizures were aborted in 66% in the VPA group and 42% in the PHT group. As a second choice in refractory patients, VPA was effective in 79% and PHT was effective in 25%. The side effects in the two groups did not differ. Sodium valproate may be preferred in convulsive SE because of its higher efficacy.

Disclosure: The authors report no conflicts of interest.

Received July 26, 2005. Accepted in final form March 20, 2006.




This article has been cited by other articles:


Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M. J Jackson
Should we accept the status quo? Time for new trials in status epilepticus
J. Neurol. Neurosurg. Psychiatry, May 1, 2008; 79(5): 490 - 490.
[Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
K. El Karoui, M. Le Quintrec, E. Dekeyser, A. Servais, A. Hummel, F. Fadel, and F. Fakhouri
Posterior reversible encephalopathy syndrome in systemic lupus erythematosus
Nephrol. Dial. Transplant., February 1, 2008; 23(2): 757 - 763.
[Full Text] [PDF]

Home page
 Age AgeingHome page
S. Beyenburg, C. Back, N. Diederich, M. Lewis, and M. Reuber
Is valproate encephalopathy under-recognised in older people? A case series
Age Ageing, May 1, 2007; 36(3): 344 - 346.
[Abstract] [Full Text] [PDF]

Home page
 J Child NeurolHome page
T. A. Glauser
Designing Practical Evidence-Based Treatment Plans for Children With Prolonged Seizures and Status Epilepticus
J Child Neurol, May 1, 2007; 22(5_suppl): 38S - 46S.
[Abstract] [PDF]

Home page
 NeurologyHome page
A. O. Rossetti, U .K. Misra, J . Kalita, and R . Patel
Sodium valproate vs phenytoin in status epilepticus: A pilot study
Neurology, February 27, 2007; 68(9): 709 - 709.
[Full Text] [PDF]

Correspondence:

Read all Correspondence

Sodium valproate vs phenytoin in status epilepticus: A pilot study
Andrea O. Rossetti
Neurology Online, 19 Sep 2006 [Full text]
Reply from the Authors
Usha Kant Misra, et al.
Neurology Online, 19 Sep 2006 [Full text]

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by AAN Enterprises, Inc.