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NEUROLOGY 2006;67:666-672
© 2006 American Academy of Neurology


Historical Neurology

Hughlings Jackson's clinical research

Evidence from contemporary documents Michael Swash, MD and Jonathan Evans, BA

From the Department of Neurology and Archives and Museum, Royal London Hospital, UK.

Address correspondence and reprint requests to Dr. M. Swash, Royal London Hospital, London E1 1BB, UK; e-mail: mswash{at}btinternet.com.

Because Hughlings Jackson directed that his personal documents be destroyed upon his death, none of his own clinical records are known. However, we have discovered several pages of notes in the Royal London Hospital Archive written in 1893 by Jackson to his House Physician at Queen Square concerning his proposals for investigation of a patient with external ophthalmoplegia. We have linked this document to JC, a patient described by Jackson in Neurological Fragments, in papers published in the Lancet between 1895 and 1909. We have followed Jackson's analysis of JC through the clinical records at the London Hospital and at Queen Square. These documents illuminate the clinical and academic background to Jackson's neurological practice in late nineteenth-century London.


Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the August 22 issue to find the title link for this article.

Disclosure: The authors report no conflicts of interest.

Received September 5, 2005.

Accepted in final form May 1, 2006.