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Gender differences in spontaneous cervical artery dissection

From Assistance Publique (M.A., K.B., M.-G.B.), Hôpitaux de Paris, Department of Neurology, University Hospital Lariboisière Paris, France; and Departments of Neurology, University Hospital Berne (M.A., L.K., B.K.) and Zurich (D.G., R.W.B.), Switzerland.

Address correspondence and reprint requests to Dr. Marcel Arnold, University Hospital Berne, Department of Neurology, Inselspital, Freiburgstrasse, 3010 Berne, Switzerland; e-mail: marcel.arnold{at}insel.ch

We analyzed sex differences in 696 patients with spontaneous cervical artery dissection. There were more men (n = 399; p < 0.0001), and men showed a higher frequency of hypertension (31% vs 15%; p < 0.0001). Women were younger (42.5 ± 9.9 vs 47.5 ± 9.3 years; p < 0.0001), had more often multiple dissections (18 vs 10%; p = 0.001), migraine (47 vs 20%; p < 0.0001), and tinnitus (16 vs 8%; p = 0.001). Outcome and mortality were similar in both sexes.

Editorial, see page 932

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the September 26 issue to find the title link for this article.

Supported by a grant from Olga-Mayenfisch-Foundation, Zurich, and Novartis Foundation, Basel.

Disclosure: The authors report no conflicts of interest.

Received December 20, 2005. Accepted in final form May 3, 2006.

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