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From the Department of Neurology (V.D., P.S.F., D.T., D.B.F., B.M.K., G.P.C., K.M.H.), College of Medicine and Neurology Service, University of Florida and Department of Veteran Affairs, Malcolm Randall Medical Center, Gainesville, FL; and the Department of Neurology (V.D.), University of Messina, Italy.
Address correspondence and reprint requests to Dr. Valeria Drago, Department of Neurology, University of Florida, College of Medicine., PO Box 100236, Gainesville, FL 32610-0236; e-mail: valeria.drago{at}neurology.ufl.edu
We evaluated the productions of an artist with frontotemporal lobar degeneration from before dementia onset until she was fully symptomatic. We noted an improvement of technique that might be related to sparing and disinhibition of the right posterior neocortex. There was a reduction of closure (completeness of the painting), possibly induced by impersistence and a decrease in evocative impact that might be explained by frontal and anterotemporal-limbic dysfunction.
Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the October 10 issue to find the title link for this article.
Supported by the Medical Research Service of the Department of Veterans Affairs and University of Messina.
Disclosure: The authors report no conflicts of interest.
Received March 15, 2006. Accepted in final form June 13, 2006.
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