Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Data Supplement
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Prehn, A. W.
Right arrow Articles by McIndoo, T. Q.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Prehn, A. W.
Right arrow Articles by McIndoo, T. Q.
Related Collections
Right arrow Parkinson's disease/Parkinsonism
Right arrow Surgery/Stimulation
NEUROLOGY 2006;67:1503-1505
© 2006 American Academy of Neurology
Brief Communications

Studying neurosurgical implants for Parkinson disease: A question of design

A. W. Prehn, PhD, D. E. Vawter, PhD, K. G. Gervais, PhD, R. G. DeVries, PhD, J. E. Garrett, JD, T. B. Freeman, MD and T. Q. McIndoo, MA

From the Minnesota Center for Health Care Ethics (A.W.P., D.E.V., K.G.G., J.E.G., T.Q.M.), Minneapolis, MN; St. Olaf College (R.G.D.), Northfield, MN; and University of South Florida (T.B.F.), Tampa, FL.

Address correspondence and reprint requests to Dr. Angela Witt Prehn, Minnesota Center for Health Care Ethics, 601 25th Avenue South, Minneapolis, MN 55454; e-mail: prehn{at}stolaf.edu.

North American researchers' perspectives on designing neurosurgical implant studies for Parkinson disease (PD) challenged the custom of holding surgical trials to less stringent evidentiary standards than other clinical studies. Researchers supported placebo surgery–controlled trials. The framework they used to design and evaluate studies both of deep brain stimulation and cellular implants for PD may be applicable to a broad range of surgical implants for other disorders.

Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the October 24 issue to find the title link for this article.

Supported by grant NS40883 from the National Institute for Neurological Disorders and Stroke, NIH.

Disclosure: The authors report no conflicts of interest.

The content of this publication does not necessarily reflect the views or policies of the U.S. Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. government.

Received October 7, 2005. Accepted in final form June 28, 2006.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by AAN Enterprises, Inc.