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Vertebral artery hypoplasia

A predisposing factor for posterior circulation stroke?

From the Department of Neurology, HUG, University Hospital of Geneva and Medical School, Geneva, Switzerland.

Address correspondence and reprint requests to Dr. F. Perren, Department of Neurology, HUG, University Hospital and Medical School of Geneva, Micheli-du-Crest 24, CH-1211 Geneva 14, Switzerland; e-mail: Fabienne.Perren{at}hcuge.ch

We determined in 725 sequentially admitted first-ever stroke patients, using color-coded duplex flow imaging of the V2 segment, whether vertebral artery hypoplasia (VAH) (diameter 2.5 mm) was more frequent (13%) in posterior circulation territory infarction (247) than in strokes in other territories (4.6%). This difference is significant (p < 0.001), whereas all other risk factors (hypertension, hyperlipidemia, diabetes, smoking) were equally (p > 0.05) distributed. Patients with VAH may be predisposed to stroke in the posterior circulation.

Disclosure: The authors report no conflicts of interest.

Received March 9, 2006. Accepted in final form September 25, 2006.

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