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From the Departments of Neurology (W.J.D., M.J.C.), Neurosurgery (M.M.), and Radiology (N.M.T.), University of Melbourne, St Vincents Hospital; the Departments of Medicine and Surgery (T.J.O.), The Royal Melbourne Hospital, University of Melbourne; and the Department of Neurosciences (W.J.D.), The Alfred Hospital, Melbourne, Victoria, Australia.
Address correspondence and reprint requests to Dr. Wendyl DSouza, The University of Melbourne, The Department of Neurology & Neurological Research, 5th Floor, The Daly Wing, St Vincents Hospital Melbourne, PO Box 2900, Fitzroy 3065, Melbourne, Victoria, Australia; e-mail: dsouzaw{at}iprimus.com.au
We report three patients with reflex toothbrushing-induced epilepsy associated with small circumscribed structural lesions in the primary somatosensory cortex in close proximity to the hand and speech motor areas. Sensory symptoms were observed at clinical onset with localizing focal ictal and interictal epileptiform discharges on EEG. These cases refine the localization, possible mechanisms of epileptogenesis, and classification of this reflex epilepsy.
Supported by The Royal Australasian College of Physicians Glaxo-Smith-Kline Fellowship in Neurology (W.J.D.).
Disclosure: The authors report no conflicts of interest.
Received July 4, 2006. Accepted in final form November 6, 2006.
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