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From the Department of Neurology, Graduate School of Medicine, Chiba University, Inohana, Chuo-ku, Chiba, Japan (M.M., S.K., T.H.); and Department of Neurology, Kameda Medical Center, Higashi-cho, Kamogawa-shi, Chiba, Japan (T.F.).
Address correspondence and reprint requests to Dr. Masahiro Mori, Department of Neurology, Graduate School of Medicine, Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba, 260-8670 Japan; e-mail: morim{at}faculty.chiba-u.jp
We analyzed clinical recovery of 92 patients with Miller Fisher syndrome who had been treated with IV immunoglobulin (IVIg; n = 28), plasmapheresis (n = 23), and no immune treatment (n = 41). IVIg slightly hastened the amelioration of ophthalmoplegia and ataxia, but the times of the disappearances of those symptoms were similar among three groups. In Miller Fisher syndrome, IVIg and plasmapheresis seem not to have influenced patients' outcomes, presumably because of good natural recovery.
Additional material related to this article can be found on the Neurology Web site. Go to www.neurology.org and scroll down the Table of Contents for the April 3 issue to find the title link for this article.
Supported in part by a Neuroimmunological Disease Research Committee grant from the Ministry of Health, Labor and Welfare, Japan.
Disclosure: The authors report no conflicts of interest.
Received June 14, 2006. Accepted in final form November 27, 2006.
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